The other feature film nominees were "City of God," "Love and Diane" and "Wonderland."
The film acting nominees were Benicio Del Torro ("21 Grams"); Holly Hunter ("Thirteen"); Dylan McDermott ("Wonderland"); Nikki Reed ("Thirteen") and Evan Rachel Wood ("Thirteen").
Television comedy episodes nominated were from "Girlfriends," "Grounded for Life," "Half & Half," "Reba" and "Run of the House."
Television dramas were nominated for both single episodes — "Boston Public," "The District," "Law & Order: SVU," "NYPD Blue" and "The Practice" — and multi-episode storylines — "The Division," "Judging Amy," "Queer as Folk," "Six Feet Under" and "Third Watch."
The awards will be presented April 29 at the Hollywood Palladium and be shown May 16 on cable's FX channel.
"We're encouraged by the increase in the number of television programs and movies that have addressed substance abuse issues during 2003," said Brian Dyak, president and chief executive officer of the Entertainment Industries Council, which presents the awards in partnership with The Robert Wood Johnson Foundation and National Institute on Drug Abuse.
"This year's PRISM nominated productions are not only a reflection of some of the most important issues threatening society today, but they also reflect the determination on the part of the entertainment industry to act responsibly when dealing with these important topics," Dyak said.